ProtEra offers the determination of protein solution structures by NMR and of crystallized proteins by X-ray.
De novo structure determination of unknown proteins with no homology to existing protein structures is readily achieved by innovative NMR spectroscopy and by X-ray.
ProtEra scientists have the knowledge for solving by NMR the solution structure of proteins even larger than 30,000 Da. Mobility studies in solution are generally routinely performed. X-ray analysis can be run on proteins in the crystal state.

NMR Methodology:
ProtEra has exclusive access to the most advanced NMR instrumentation (900 MHz and 800 MHz NMR equipped with cryoprobes).

MAIN STEPS - Optimization of sample condition - Backbone resonance assignments - Side chain resonance assignments - Structure calculation